MFZ 10-7 是 mGluR5 的负变构调节剂。 在大鼠中，MFZ 10-7 (i.p.) 抑制可卡因诱导的药物寻求行为恢复、可卡因相关线索诱导的可卡因寻求行为和静脉内可卡因自我给药。

MFZ 10-7 is anegative allosteric modulator of the mGluR5. In rats, MFZ 10-7 (i.p.) inhibits cocaine-induced reinstatement of drug-seeking behavior, cocaine-associated cue-induced cocaine-seeking behavior and intravenous cocaine self-administration.

1224431-15-5

C15H9FN2

236.24

MFZ 10-7

Ethanol:<27.27mg/ml
DMSO:<27.27mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years