5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole 是一种基于 3-Br-isoxazoline 的疟原虫抑制剂恶性疟原虫(D10 和 W2 菌株)和利什曼原虫属。 (L. infantum 和 L.tropica) 前鞭毛体,IC50 为 0.035、0.058、3.5 和 7.5 μM。
产品描述
5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.
Cas No.
T9858
分子式
C15H16BrN3O2
分子量
350.21
别名
5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years