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Ibutilide fumarate(U70226E)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ibutilide fumarate(U70226E)图片
CAS NO:122647-32-9
规格:≥98%
包装与价格:
包装价格(元)
5mg询价
10mg询价
25mg询价
50mg询价
100mg询价
500mg询价
1g询价

理化性质和储存条件
Molecular Weight (MW)885.23
Formula(C20H36N2O3S)2.C4H4O4
CAS No.122647-32-9
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 89 mg/mL (100.5 mM)
Water: 89 mg/mL (100.5 mM)
Ethanol: 89 mg/mL (100.5 mM)
Other info

Chemical Name: N-[4-[4-[ethyl(heptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide

InChi Key: ALOBUEHUHMBRLE-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3

SMILES Code: CS(=O)(NC1=CC=C(C(O)CCCN(CC)CCCCCCC)C=C1)=O

SynonymsU70226E; U 70226E; U70226 E; U 70226 E; U-70226-E; U-70226E
实验参考方法
In Vitro

In vitro activity: Ibutilide protected against H2O2-induced cardiomyocytes injury through inhibiting endoplasmic reticulum and mitochondrial stress pathways.

In VivoIbutilide significantly decreased defibrillation threshold through the reduction of activation pattern complexity during ventricular fibrillation in canine hearts.
Animal model
Formulation & Dosage
References

Chin Med J (Engl). 125, 2701-2707.

 
 
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