X1 compound 结合抑制组蛋白 H3K27 三甲基化并阻断 X 染色体失活的起始。 X1 compound 结合减少了 RepA 的构象空间并取代了同源相互作用的蛋白质因子，包括 PRC2 和 SPEN。
产品描述
X1 compound binding suppresses histone H3K27 trimethylation and blocks initiation of X-chromosome inactivation. X1 compound binding reduces the conformational space of RepA and displaces cognate interacting protein factors including PRC2 and SPEN.
Cas No.
T60044
分子式
C27H20N4O
分子量
416.48
别名
X1 compound
储存和溶解度
H2O:Insoluble
DMSO:80 mg/mL(192.09 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
