MtTMPK-IN-1 (compound 3) 一种有效的分支杆菌胸苷酸激酶 (MtbTMPK)抑制剂，IC50为 2.5 μM。MtTMPK-IN-1 对MtbH37Rv 具有中等至微弱的抑制活性，对人成纤维细胞 MRC-5 具有低细胞毒性。MtTMPK-IN-1 可用于结核病的研究。
产品描述
MtTMPK-IN-1 (compound 3) is a potent Mycobacterium tuberculosis thymidylate kinase ( Mt TMPK) inhibitor with an IC 50 value of 2.5 μM. MtTMPK-IN-1 has moderate to weak activity against Mtb H37Rv and low cytotoxicity in human fibroblast cells MRC-5. MtTMPK-IN-1 can be used for researching tuberculosis [1].
分子式
C22H24N4O3
分子量
392.45
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
