Arimoclomol citrate (BRX-220 citrate) is a co-inducer of heat shock proteins ( HSP ). Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.

Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis[1]. Animal Model: Male Wistar rats weighing 240 to 270 g[1]Dosage: 20 mg/kg Administration: Administered intragastrically, for 5 days Result: Had a protective effect against CCK-induced acute pancreatitis.

368860-21-3

C20H28ClN3O10

505.9

Arimoclomol citrate;BRX-220 citrate;Arimoclomol citrate

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years