Sardomozide 是 S-腺苷甲硫氨酸脱羧酶 (SAMDC) 的抑制剂 (IC50 = 5 nM)。
产品描述
Sardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).
体外活性
In CHO/664 cells treated with DENSPM, Sardomozide inhibits cell growth without vacuole formation[1]. Sardomozide (3 μM) reduces intracellular SAMDC activity to 10%[2].
Cas No.
138794-73-7
分子式
C11H16Cl2N6
分子量
303.19
别名
CGP 48664 dihydrochloride;Sardomozide
储存和溶解度
H2O:10 mg/mL (32.98 mM),Need ultrasonic
DMSO:20 mg/mL (65.97 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
