Bendazac 是一种氧乙酸，具有抗过敏、抗炎、利胆和抗血脂作用。它能够阻断蛋白质变性，延缓白内障的发生过程。
产品描述
Bendazac is an anticataract drug. It may act by preventing protein denaturation.
体外活性
Bendazac (bendazac L-lysine and sodium) inhibits the early stages of protein glycation, as well as the formation of fluorescent advanced glycation products.?Bendazac lysine (20 mM) proved to be more effective in inhibiting fluorescence development (67% inhibition) that the corresponding sodium salt (35% inhibition).?No significant differences were found with respect to furosine levels ;?about 40% inhibition was produced with either bendazac lysine or sodium salt bendazac clearly inhibits glycation of human lens crystallins, as can be efficiently monitored by following specific changes in lens protein fluorescence[1]
Cas No.
20187-55-7
分子式
C16H14N2O3
分子量
282.299
别名
AF-983;Bendazolic acid;Bendazac
储存和溶解度
DMSO:56 mg/mL (198.38 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
