Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.

49852-81-5

C21H34O5

366.498

Prostaglandin D2 methyl ester;Prostaglandin D2 methyl ester

DMSO:50 mg/mL
PBS (pH 7.2):1 mg/mL
Ethanol:50 mg/mL
DMF:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years