KRAS G12C inhibitor 43 (compound 59) 是一种有效KRAS G12C抑制剂。KRAS G12C inhibitor 43 对 H358, A549, HCC 细胞具有抗迁移和抗增殖活性，IC50s 分别为 0.001-1 μM, >1 μM, >1 μM。

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC 50 s of 0.001-1 μM, >1 μM, >1 μM for H358, A549, HCC cells,respectively [1].

2648808-69-7

C33H35N7O3

577.68

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years