PDZ1i 是一种有效的，透过血脑屏障的，特异性的MDA-9/Syntenin抑制剂。PDZ1i 可抑制关键的 GBM (多形性成胶质细胞瘤)信号，包括FAK和EGFRvIII。PDZ1i 可降低MMP分泌。PDZ1i 能提高患脑瘤小鼠的生存率并减少肿瘤的侵袭。
产品描述
PDZ1i is a potent, BBB-penetrated and specific MDA-9/Syntenin inhibitor. PDZ1i inhibits crucial GBM (glioblastoma multiforme) signaling involving FAK and EGFRvIII. PDZ1i reduces MMP secretion. PDZ1i can improve survival of brain tumor-bearing mice and reduce tumor invasion [1].
Cas No.
2083618-79-3
分子式
C28H26N8O4
分子量
538.56
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
