PARP1-IN-9 (Compound 5c) 是一种PARP1抑制剂,IC50值为 30.51 nM。PARP1-IN-9 诱导细胞凋亡(Apoptosis),具有抗癌活性。PARP1-IN-9 具有高于 Olaparib 的效果。
产品描述
PARP1-IN-9 (Compound 5c) is a PARP1 inhibitor with an IC 50 of 30.51 nM. PARP1-IN-9 induces cell apoptosis and shows anticancer activity. PARP1-IN-9 has higher potency than Olaparib [1].
体外活性
PARP1-IN-9 (Compound 5c) shows antiproliferative activity with an IC 50 of 3.65 μM against MDA-MB-436 cancer cell line [1].
Cas No.
2494000-71-2
分子式
C18H21N3O5
分子量
359.38
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years