THIP 是一种选择性δ-GABAAR激动剂，功能选择性 GABAAR 配体，对 αβγ 和 α4β2δ GABAARs 表现出弱拮抗作用，对 α4β1δ 和 α4β3δ 表现出激动作用。
产品描述
THIP has a strong affinity for the δ subunit of GABAA receptors. THIP is a functionally selective GABAAR ligand, agonistic to α4β1δ, α4β3δ, and weakly antagonistic to αβγ and α4β2δ GABAARs.
Cas No.
64603-91-4
分子式
C6H8N2O2
分子量
140.14
别名
加波沙朵;Gaboxadol;Gaboxadolum;THIP
储存和溶解度
DMSO:100 mg/mL (570.86 mM),ultrasonic and adjust pH to 3 with HCl
H2O:20 mg/mL (142.71 mM),Need ultrasonic
Ethanol:1 mg/mL (5.71 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
