产品描述
DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
体外活性
DB07107 from DrugBank showed the highest binding energy (XP: -14.045 kcal/mol). DB07107 is more potent in blocking drug-resistant T315I mutant than the wild-type Bcr-Abl [1].
Cas No.
552332-71-5
分子式
C23H22N4O
分子量
370.45
别名
DB07107
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
