产品描述
TAK-441 is a potent inhibitor of the Hedgehog (Hh) signaling pathway. TAK-441 shows activity to suppress transcription factor Gli1 mRNA expression in tumor-associated stromal tissue and inhibited tumor growth (treatment/control ratio, 3%) in a mouse medulloblastoma allograft model.
Cas No.
1186231-83-3
分子式
C28H31F3N4O6
分子量
576.56
别名
TAK441;TAK-441
储存和溶解度
H2O:Insoluble
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
