HIV-1 inhibitor-30 (compound 10i) 是一种有效的HIV-1抑制剂，对 HIV-1 的EC50为 40 nM，对 HIV-1 RT DNA聚合酶的IC50为 80 nM。HIV-1 inhibitor-30 对 7 种非核苷逆转录酶抑制剂 (NNRTI) 耐药的 HIV-1 菌株 (RT-K103N; RT-Y181C; RT-K103N,Y181C; RT-L100I,K103N; RT-Y188L; RT-K103N,G190A; RT-K103N,V108I) 具有较高的抗逆转录病毒活性，IC50为 0.04~1.42 μM。

HIV-1 inhibitor-30 (compound 10i) is a potent HIV-1 inhibitor with an EC 50 value of 40 nM and an IC 50 value of 80 nM for HIV-1 RT DNA polymerase. HIV-1 inhibitor-30 has highly antiretroviral activity against seven non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 strains (RT-K103N; RT-Y181C; RT-K103N,Y181C; RT-L100I,K103N; RT-Y188L; RT-K103N,G190A; RT-K103N,V108I) with IC 50 s of 0.04~1.42 μM. HIV-1 inhibitor-30 can be used for researching AIDS [1].

2132412-77-0

C19H20ClN3O2

357.83

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years