PP7 是一种PB1-PB2互作抑制剂，IC50为 8.6 μM。PB1-PB2 抑制病毒聚合酶的活性，IC50为9.5 μM。它对甲型流感病毒 A 包括 (H1N1)pdm09 (EC50=1.4 μM)，A(H7N9)，A(H9N2) 亚型具有抗病毒活性。
产品描述
PP7 is a potent inhibitor of PB1-PB2 interaction(IC50 of 8.6 μM).
体外活性
PP7 showed inhibition against viral polymerase activity (IC50=9.5 μM). PP7 exhibited antiviral activities against influenza virus subtypes A (H1N1)pdm09(EC50=1.4 μM), A(H7N9) and A(H9N2) in cell cultures[1].
Cas No.
433238-84-7
分子式
C18H14Cl2N2O3
分子量
377.22
别名
PP7
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
