SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement.

SENP1-IN-3 improves the sensitivity of tumor cells to irradiation[1]. SENP1-IN-3 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC 50 of >20μM[1]. Cell Cytotoxicity Assay[1]Cell Line: Hela cells Concentration: 0.7 μM, 2.2 μM, 6.6 μM, 20 μM Incubation Time: 72 hours Result: IC 50 >20 μM

2416910-59-1

C36H58N2O4

582.87

SENP1-IN-3;SENP1-IN-3

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years