AS057278 是一种 D-氨基酸氧化酶 (DAAO) 抑制剂。
产品描述
AS057278 is an D-amino acid oxidase (DAAO) inhibitor.
体内活性
AS057278 was able to normalize phencyclidine (PCP)-induced prepulse inhibition after acute (80 mg/kg) and chronic (20 mg/kg b.i.d.) oral administration in mice.?AS057278 after oral chronic treatment (10 mg/kg b.i.d.) was able to normalize PCP-induced hyperlocomotion.?AS057278 has the potential to anti-psychotic action toward both cognitive and positive symptoms of schizophrenia[1].
Cas No.
402-61-9
分子式
C5H6N2O2
分子量
126.115
别名
5-甲基-1H-吡唑-3-羧酸;3-Methylpyrazole-5-carboxylic acid;AS057278
储存和溶解度
DMSO:25mg/mL(198.24mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
