CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).

CDK9-IN-9 (example 2) inhibits the proliferation of HeLa, HeLa-MaTu-ADR, DU145, NCI-H460, Caco-2, B16F10, A2780 and MOLM-13 cells (IC50s: 4.4 nM, 5.3 nM, 4.5 nM, 9.2 nM, 8.4 nM, 1.2 nM, 1.2 nM, 2.0 nM).

2246956-84-1

C22H23F2N5O2S

459.51

CDK9-IN-9

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years