Mal-amIDO-PEG7-acid 是一种基于 PEG 的 PROTAC linker,可用于合成 PROTAC。
产品描述
Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
体外活性
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].
Cas No.
2112731-42-5
分子式
C24H40N2O12
分子量
548.58
别名
Mal-NH-PEG7-COOH;Maleimide-NH-PEG7-CH2CH2COOH;Mal-amido-PEG7-acid
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years