Montelukast (also known as
MK-476; MK 476; MK0476; trade names Singulair; Monteflo; Lukotas;
Lumona) is a novel, potent, selective CysLT1 (leukotriene receptor)
receptor antagonist used for the maintenance treatment of asthma and to
relieve symptoms of seasonal allergies. Montelukast blocks the action of
leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl
leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding
to it. This reduces the bronchoconstriction otherwise caused by the
leukotriene and results in less inflammation.
纯度：≥98%
CAS：158966-92-8
