7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.

115453-82-2

C12H9F3O3

258.19

7-Ethoxy-4-(trifluoromethyl)coumarin

Chloroform:Slightly soluble
Methanol:Slightly soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years