FAK-IN-8 (化合物 5h) 是一种FAK抑制剂 (IC50=5.32 μM)。FAK-IN-8 具有较好的抗增殖活性,可用于癌症的研究。
产品描述
FAK-IN-8 (compound 5h) is a FAK inhibitor ( IC 50 =5.32 μM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research [1].
体外活性
FAK-IN-8 (0-10 μM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation [1]. Cell Proliferation Assay [1] Cell Line: MCF-7 and B16-F10 cells Concentration: 0-10 μM Incubation Time: 48 h Result: Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC 50 values of 3.57 and 3.52 μM, respectively.
Cas No.
1374959-91-7
分子式
C15H9Cl2N3O2S
分子量
366.22
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years