CAY10771 is a dual agonist of farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor δ (PPARδ).1It activates FXR and PPARδ in reporter assays using HEK293T cells (EC50s = 0.94 and 1.5 μM, respectively) and is selective for these receptors over retinoic acid receptor α (RARα), retinoid X receptor α (RXRα), PPARα, PPARγ, and liver X receptor α (LXRα) at 10 μM.

2522599-79-5

C28H25Cl3N2O4

559.87

CAY10771

Acetonitrile:5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years