Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes through phosphoinositide turnover. Ganglioside GQ1b mixture contains ganglioside GQ1b molecular species with C18:1 and C20:1 sphingoid backbones.

68652-37-9

C106H178N6O55?4Na (for Sphingosine C18:1)

2508.5

Ganglioside GQ1b Mixture (sodium salt)

Chloroform:Methanol (2:1):Soluble
H2O:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years