Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. 17-phenyl trinor PGF2α methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

38315-47-8

C24H34O5

402.531

17-phenyl trinor Prostaglandin F2α methyl ester;17-phenyl trinor Prostaglandin F2α methyl ester

Acetonitrile:3 mg/mL
DMSO:25 mg/mL
DMF:25 mg/mL
PBS (pH 7.2):0.25 mg/mL
Ethanol:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years