Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

70274-78-1

C18H25ClN6O4

424.89

Gly-Arg-AMC (hydrochloride)

Ethanol:20 mg/mL
DMSO:PBS (pH 7.2) (1:1):0.5 mg/mL
DMF:30 mg/mL
DMSO:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years