产品描述
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
Cas No.
130743-07-6
分子式
C62H78N14O14
分子量
1243.37
别名
Quinaldopeptin
储存和溶解度
DMF:Soluble
Ethanol:Slightly soluble
DMSO:Soluble
Methanol:Slightly soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
