Eicosapentaenoic acid ethyl ester 是 一种ω-3 脂肪酸剂和人内源性代谢物。
产品描述
Eicosapentaenoic acid ethyl ester is an omega-3 fatty acid.
体内活性
Icosapent ethyl (IPE) 4 g/day significantly reduced large VLDL, total LDL, small LDL, and total HDL particle concentrations and VLDL particle size in patients with TG 500 mg/dL.Changes in VLDL particle concentration and size reflect the TG-lowering effects of eicosapentaenoic acid.?The reduction in LDL particle concentration with IPE is novel among ω-3 therapies and is consistent with the previously reported reduction in apolipoprotein B and lack of LDL-C increase with IPE in patients with very high TG levels.
Cas No.
86227-47-6
分子式
C22H34O2
分子量
330.512
别名
顺-二十碳五烯酸乙酯;Ethyl eicosapentaenoate;EPA ethyl ester;Icosapent ethyl;Eicosapentaenoic acid ethyl ester
储存和溶解度
Ethanol:50 mg/mL (151.29 mM),Need ultrasonic
DMSO:33.33 mg/mL (100.85 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years