GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane domain located within 20 amino acids of the C-terminus of the light chain.

The GPllb-IIa complex is a Ca2+-dependent heterodimer that, on activated platelets, can bind one of the four different adhesive proteins. (i.e. fibrinogen, fibronectin, von Willebrand factor, or vitronectin ).

TP2198

C47H75N17O20

1198.2

Platelet Membrane Glycoprotein IIB Peptide (296-306)

DMSO:≥119.8mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years