Ibiglustat L-Malic acid (Venglustat; GZ402671; Genz-682452; GZ-452; SAR-402671) is a novel and potent inhibitor of glucosylceramide synthase (GCS) and also a ceramide glucosyltransferase inhibitor. It has the potential to be used for Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3.

纯度：≥98%

CAS：1629063-78-0