GSK3368715 dihydrochloride (GSK-3368715; EPZ-019997; EPZ019997), the dihydrochloride salt of GSK3368715, is a potent and orally bioavailable inhibitor of type I PRMTs (protein arginine methyltransferases) with potential anticancer activity. It inhibits PRMT1/3/4/6/8 with IC50s of 3.1 nM, 48 nM, 1148 nM, 5.7 nM, 1.7 nM, respectively.
纯度:≥98%
CAS:1628925-77-8