This product is discontinued due to commercial reason. Rac-Nedisertib (Rac-M3814) is a racemate of Nedisertib. Nedisertib (M-3814, MSC-2490484A) is a
poten, selective and orally bioavailable inhibitor of DNA-dependent
protein kinase (DNA-PK) with an IC50 of<3
nM and with potential antineoplastic and chemo/radiosensitizing
activities. Upon oral administration, the DNA-PK inhibitor MSC2490484A
binds to and inhibits the activity of DNA-PK. This inhibits the ability
of tumor cells to repair damaged DNA, which may lead to a reduction in
cellular proliferation of cancer cells expressing DNA-PK.
纯度：≥98%
CAS：1637542-34-7
