GPI-1046 (GPI1046) is an immunophilin ligand that can reduce ethanol consumption in part through activation of GLT1 in alcohol-preferring rats. GPI-1046 shows neuroprotective effects in neurodegenerative disease models. However, GPI-1046 does not have regenerative effects in MPTP-treated primates and suggest that there may be species differences with respect to the trophic effects of GPI-1046 on nigrostriatal DA neurons.
纯度:≥98%
CAS:186452-09-5