Ciclesonide is an inhaled corticosteroids, used to ameliorate symptoms of airway inflammatory diseases, such as asthma, allergic rhinitis, and chronic obstructive pulmonary disease. Ciclesonide is a corticosteroid prodrug that is converted to its active form, desisobutyryl-CIC. Des-CIC is a glucocorticoid receptor agonist. References: Sun YH, Ge LT, Jiang JX, Shen HJ, Jia YL, Dong XW, Sun Y, Xie QM. Formoterol
synergy with des-ciclesonide inhibits IL-4 expression in IgE/antigen-induced mast
cells by inhibiting JNK activation. Eur J Pharmacol. 2015 Aug 15;76161-7. doi:
10.1016/j.ejphar.2015.05.008. Epub 2015 May 19. PubMed PMID: 26003274.
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CAS:126544-47-6