阿托伐醌(Atovaquone,95233-18-4) blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.
| 中文别名 | 阿托伐醌(Atovaquone,95233-18-4);阿托喹酮(标准品);2-(反式-4-(4-氯苯基)环己基)-3-羟基-1,4-萘二酮;阿托喹酮;阿托伐醌;阿托伐醌 -D4 |
| 英文别名 | Atovaquone(阿托伐醌,95233-18-4);3-[4-(4-Chlorophenyl)cyclohexyl]-4-hydroxy-1,2-naphthalenedione |
| CAS号 | 95233-18-4 |
| SMILES | O=C1C([C@H]2CC[C@H](C3=CC=C(Cl)C=C3)CC2)=C(O)C(C4=C1C=CC=C4)=O |
| Inchi | InChI=1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,24H,5-8H2 |
| InchiKey | BSJMWHQBCZFXBR-UHFFFAOYSA-N |
| 分子式 Formula | C22H19ClO3 |
| 分子量 Molecular Weight | 366.84 |
| 熔点 Melting point | 216-2190C |
| 沸点 Boiling point | 535.0±50.0 ℃(Predicted) |
| 密度 Density | 1.349±0.06 g/cm3(Predicted) |
| 溶解度Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| 性状 | 固体粉末,Power |
| 储藏条件 Storage conditions | -20℃ 3 years年 4℃ 2 years年 / In solvent溶液中:-80℃ 6 months月 -20℃ 1 month月 |
