CI 951 is a novel dihydronaphthyridine Ca2+ antagonist, channel blocker. CI-951 may be a useful therapeutic agent for focal cerebral ischemia. It has potential as a cerebral vasodilator. References: Knight WA, Hart KW, Adeoye OM, Bonomo JB, Keegan SP, Ficker DM, Szaflarski JP, Privitera MD, Lindsell CJ. The incidence of seizures in patients undergoing therapeutic hypothermia after resuscitation from cardiac arrest. Epilepsy Res. 2013 Oct;106(3):396-402. doi: 10.1016/j.eplepsyres.2013.06.018. Epub 2013 Jul 29. PubMed PMID: 23906560; PubMed Central PMCID: PMC3961478.
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CAS:126661-07-2