TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 of 0.55 μM and 10.2 μM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes. References: Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.
纯度:≥98%
CAS:519178-28-0