PU-H54 is a purine-based inhibitor of Grp94. Specifically, it is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 subpocket in Grp94. References: Khandelwal A, Crowley VM, Blagg BSJ. Resorcinol-Based Grp94-Selective Inhibitors. ACS Medicinal Chemistry Letters. 2017 September 1. doi: 10.1021/acsmedchemlett.7b00193
纯度:≥98%
CAS:1454619-13-6