生物活性
Zearalenone是通常由镰刀菌属物种产生的一种植物雌激素真菌毒素，被证明是一种细胞毒性化合物，但芦荟结合雌激素受体（ER）（ERβ和ERα的IC50值分别为166和240 nM），并被发现可以刺激转录。两种亚型的活性在1-10 nM之间。
化学数据
| 目录号 | A13740 |
| M. Wt | 318.36 |
| Formula | C18H22O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 17924-92-4 |
| SMILES | C[C@H]1CCCC(=O)CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O |
溶解度
| In vitro | DMSO | 56 mg/mL (175.9 mM) |
| Water | Insoluble |
| Ethanol | 56 mg/mL (175.9 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 31.41 mL | 157.05 mL | 314.11 mL |
| 0.5 mM | 6.28 mL | 31.41 mL | 62.82 mL |
| 1 mM | 3.14 mL | 15.71 mL | 31.41 mL |
| 5 mM | 0.63 mL | 3.14 mL | 6.28 mL |
*The above data is based on the productmolecular weight 318.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
