Olsalazine Dipotassium (CJ-91B) is a potent anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.Olsalazine displays multiple effects on intestinal electrolyte. In vitro application of Olsalazine (< 2.89 mM) increases the secretion of both sodium and chloride ions and decreases chloride ion absorption in rat and rabbit ileal mucosa. Concentration of Olsalazine < 11.5 mM also dose-dependently decreases net sodium and, to a greater degree, chloride absorption in the isolated rat colon. Potassium secretion is also increases but only at a high Olsalazine concentration (11.5 mM).
纯度:≥98%