CAS NO: | 26095-59-0 |
规格: | ≥98% |
包装 | 价格(元) |
10mg | 询价 |
25mg | 询价 |
50mg | 询价 |
100mg | 询价 |
250mg | 询价 |
500mg | 询价 |
1g | 询价 |
Molecular Weight (MW) | 563.57 |
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Formula | C29H43BrN2O4 |
CAS No. | 26095-59-0 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: 113 mg/mL (200.5 mM) |
Water: 113 mg/mL (200.5 mM) | |
Ethanol: 113 mg/mL (200.5 mM) | |
SMILES | O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-] |
Synonyms | SP-63; Octylonium bromide; SP 63; SP63; |
In Vitro | In vitro activity: Otilonium bromide is a quaternary ammonium compound whose spasmolytic action, selective on the distal gastrointestinal tract, is mainly due to its direct myolytic properties. This drug modifies Ca2+ fluxes from extracellular and intracellular pools in the intestinal smooth muscle and is poorly absorbed, thus it exerts its action locally, without any considerable systemic effect. |
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In Vivo | |
Animal model | |
Formulation & Dosage | |
References | Arch Int Pharmacodyn Ther. 1983 Aug;264(2):305-23; Aliment Pharmacol Ther. 1998 Oct;12(10):1003-10. |
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