生物活性
Indiplon是吡唑并嘧啶，可作为GABAA受体的高亲和力正变构调节剂，以剂量依赖和可逆的方式增强GABA活化的氯离子电流。
化学数据
| 目录号 | A13769 |
| 作用机制 | Modulator (调节剂) |
| M. Wt | 376.4 |
| Formula | C20H16N4O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 325715-02-4 |
| Synonyms | NBI 34060 |
| SMILES | CC(=O)N(C)C1=CC=CC(=C1)C2=CC=NC3=C(C=NN23)C(=O)C4=CC=CS4 |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 26.57 mL | 132.84 mL | 265.67 mL |
| 0.5 mM | 5.31 mL | 26.57 mL | 53.13 mL |
| 1 mM | 2.66 mL | 13.28 mL | 26.57 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.31 mL |
*The above data is based on the productmolecular weight 376.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
