Mitiglinide Calcium(KAD-1229)
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| CAS NO: | 145525-41-3 |
| 规格: | ≥98% |
包装与价格：
| 包装 | 价格(元) |
| 50mg | 询价 |
| 100mg | 询价 |
| 250mg | 询价 |
| 500mg | 询价 |
| 1g | 询价 |
| 5g | 询价 |
| 10g | 询价 |
理化性质和储存条件
| Molecular Weight (MW) | 668.88 |
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| Formula | (C19H24NO3)2.Ca |
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| CAS No. | 145525-41-3 (Mitiglinide Calcium) |
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| Storage | -20℃ for 3 years in powder form |
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| -80℃ for 2 years in solvent |
| Solubility (In vitro) | DMSO: <1 mg/mL |
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| Water:<1 mg/mL |
| Ethanol: 2 mg/mL (2.99 mM) |
| SMILES Code | O=C([O-])C(CC1=CC=CC=C1)CC(N2C[C@]3([H])CCCC[C@]3([H])C2)=O.O=C([O-])C(CC4=CC=CC=C4)
CC(N5C[C@]6([H])CCCC[C@]6([H])C5)=O.[Ca+2] |
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| Synonyms | KAD-1229; S 21403; KAD 1229; S21403; KAD1229; S-21403; Mitiglinide calcium; Glufast. |
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实验参考方法
| In Vitro | In vitro activity: Mitiglinide (KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value: Target: KATP channel Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)-sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. Mitiglinide stimulates insulin secretion by stimulating Ca2+ influx. |
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| In Vivo |
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| Formulation & Dosage |
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| References |
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