Piperaquine tetraphosphate tetrahydrate, a bisquinoline analog, is a potent antiparasitic agent that has been widely used in combination with other antimalarial agents such as dihydroartemisinin to treat malaria. Piperaquine was developed under the Chinese National Malaria Elimination Programme in the 1960s and was adopted throughout China as a replacement for the structurually similar antimalarial drug chloroquine. Due to widespread parasite resistance to piperaquine, the drug fell out of use as a monotherapy, and is instead used as a partner drug for artemisinin combination therapy. Piperaquine kills parasites by disrupting the detoxification of host heme.

纯度：≥98%

CAS：915967-82-7