Zorubicin is a benzoyl-hydrazone analogue of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. References: Jelic S, Kovcin V, Milanovic N, Kreacic M, Pendjer I, Jovanovic V, Ristovic Z, Opric M, Mitrovic L. Randomized study of zorubicin versus zorubicin-cisplatin in undifferentiated carcinoma of the nasopharynx (UCNT). Ann Oncol. 1997 Aug;8(8):739-44. PubMed PMID: 9332680.
纯度:≥98%
CAS:54083-22-6