Z060228 is an potent anti-HBV inhibitor. The HBV DNA replication in the supernatants of the HepG2.2.15 cells was effectively inhibited by Z060228. Z060228 exhibited effects on the self-assembly of Cp149. SEC data revealed that Z060228 altered the equilibrium (a state of stability) of Cp149 assembly. Z060228 could prevent Cp149 from self-assembling to the correct core particles. Z060228 was demonstrated to be a potential capsid targeting anti-HBV drug candidate. References: Guan H, Zhao G, Chen W, Wu G, Liu H, Jiang X, Li S, Wang LL. The novel compound Z060228 inhibits assembly of the HBV capsid. Life Sci. 2015 Jul 15;133:1-7. doi: 10.1016/j.lfs.2015.04.011. Epub 2015 Apr 25. PubMed PMID: 25921762.

纯度：≥98%

CAS：1005459-82-4