YM-440 is an insulin sensitizer potentially for the treatment of type 2 diabetes. Through research, it has proven to be a novel hypoglycemic agent by suppressing hepatic glucose output via gluconeogenesis by reducing glucose-6-phosphatase activity in obese Zucker rats. References: Nakano R, Kurosaki E, Shimaya A, Kajikawa S, Shibasaki M. YM440, a novel hypoglycemic agent, protects against nephropathy in Zucker fatty rats via plasma triglyceride reduction. Eur J Pharmacol. 2006 Nov 7;549(1-3):185-91. PubMed PMID: 16989806.
纯度:≥98%
CAS:163300-58-1