YH18968 is a GPR119 agonist, improving glucose tolerance and augmenting the glucose lowering effect. YH18968 augments the plasma level of active GLP-1 in normal mice in combination treatment with a dipeptidyl peptidase 4 (DPP-4) inhibitor. References: Han T, Lee BM, Park YH, Lee DH, Choi HH, Lee T, Kim H. YH18968, a Novel 1,2,4-Triazolone G-Protein Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes Mellitus. Biomol Ther (Seoul). 2018 Mar 1;26(2):201-209. doi: 10.4062/biomolther.2018.011. PubMed PMID: 29495245; PubMed Central PMCID: PMC5839499.
纯度:≥98%
CAS:1632498-56-6